Jason K. was 27 the first time he tried to have sex with a woman and couldn’t get an erection. He knew it wasn’t a physiological problem, because he had no problem getting hard at home while watching porn and masturbating, but the embarrassing episode gnawed at him. Jason grew anxious that it could happen again, so he decided to bring it up at his doctor’s appointment a few weeks later…
Monthly Archives: April 2018
April 2018 Entries
First Look Inside the Herpes Virus
The herpesvirus family includes herpes simplex virus type 1 (HSV-1), which causes cold sores, and type 2 (HSV-2), which causes genital herpes. Herpesviruses comprise a large DNA genome enclosed in a large and complex protein cage called a capsid (see the Perspective by Heldwein). Dai and Zhou used electron microscopy to determine a high-resolution structure of the HSV-1 capsid bound to the tegument proteins that occupy the space between the capsid and the nuclear envelope. The structure suggests how these components may play a role in viral transport. Yuan et al. describe a higher-resolution structure of an HSV-2 capsid, providing insight into how the shell assembles and is stabilized.
April 2018 Entries
Abstract: Biomolecular motors such as F1–adenosine triphosphate synthase (F1-ATPase) and myosin are similar in size, and they generate forces compatible with currently producible nanoengineered structures. We have engineered individual biomolecular motors and nanoscale inorganic systems, and we describe their integration in a hybrid nanomechanical device powered by a biomolecular motor. The device consisted of three components: an engineered substrate, an F1-ATPase biomolecular motor, and fabricated nanopropellers. Rotation of the nanopropeller was initiated with 2 mM adenosine triphosphate and inhibited by sodium azide.